Core Imaging Services

Intro

City Imaging and Clinical Labs provides comprehensive core imaging support for clinical trials, ensuring standardised image acquisition, centralised review, and regulatory-compliant data management.

Key areas:

• Protocol development & standardisation
• Site qualification & training
• Centralised blinded reads
• Imaging endpoints (RECIST, etc.)
• Secure image transfer & archiving

Standardised Imaging Protocols

Imaging procedures are performed in accordance with study-specific protocols, ensuring consistency across all trial sites. Protocols are developed, reviewed, and implemented in alignment with sponsor requirements and applicable regulatory guidelines.

Site Qualification and Training

Imaging sites undergo a structured qualification process, including equipment assessment, personnel evaluation, and protocol feasibility checks. Comprehensive training is provided to site personnel to ensure adherence to imaging protocols and quality standards.

Image Acquisition and Quality Control

All imaging data is acquired using qualified equipment and standardised procedures. Rigorous quality control checks are performed to assess image quality, protocol compliance, and data completeness prior to analysis.

Centralised Image Review and Analysis

Blinded, independent image review is conducted by experienced radiologists and imaging specialists. Standardized evaluation criteria and validated software tools are used to ensure objective and reproducible interpretation of imaging data.

Data Management and Transfer

Secure and validated systems are used for image data transfer, storage, and archival. End-to-end traceability is maintained, ensuring data integrity, confidentiality, and compliance with applicable regulatory requirements.

Regulatory Compliance and Standards

Core imaging services are aligned with international standards and guidelines, including GCP and applicable imaging and data handling regulations. All processes are designed to support regulatory submissions and audits.

Project Management and Sponsor Support

Dedicated project management teams coordinate with sponsors and clinical sites to ensure timely execution of imaging activities, milestone tracking, and effective communication throughout the study lifecycle.

What We Do

• Provide centralised imaging solutions for clinical trials across therapeutic areas
• Deliver high-quality radiology imaging including CT, MRI, X-ray, Ultrasound, and advanced modalities
• Support standardised image acquisition and interpretation protocols
• Offer centralised image review and analysis by expert radiologists
• Enable quantitative imaging endpoints for clinical research studies
• Ensure regulatory-compliant imaging workflows aligned with global trial standards
• Provide neurology and cardiology imaging assessments for specialised trials
• Support multi-site imaging standardisation across trial locations
• Deliver accurate, consistent, and reproducible imaging data
• Integrate imaging data with clinical and laboratory datasets

How We Do

• Implement standardised imaging protocols across all participating sites
• Utilise advanced imaging technologies and calibrated equipment for precision
• Conduct centralised image processing and blinded independent reviews (BIR)
• Ensure quality control through regular audits and calibration checks
• Use secure digital platforms for image transfer, storage, and analysis
• Maintain compliance with regulatory and sponsor requirements
• Provide an expert radiologist panel for consistent interpretation
• Enable real-time tracking and monitoring of imaging data
• Offer customizable imaging workflows based on study protocols
• Ensure data integrity, confidentiality, and traceability
• Integrate imaging operations with central lab services for unified trial support